Garcia-Maestas has held curatorial positions at the Denver Art Museum, the Biennial of the Americas, and MCA Denver. While at the Denver Art Museum she worked on several major exhibitions, most notably Mi Tierra: Contemporary Artists Explore Place, an exhibition featuring site-specific installations by 13 Latinx and Chicanx artists examining themes of displacement and visibility. In 2015, she co-founded the Biennial Ambassadors artist residency program, a collaboration between the Biennial of the Americas and SOMA Mexico City. Garcia-Maestas’ curated exhibitions include Diana Al-Hadid: Ash in the Trade Winds, In Some Form or Fashion, Esteban Cabeza de Baca: Let Earth Breathe, A Divided Landscape, co-curated with Neville Wakefield, Yvette Mayorga: What a Time to Be, and recently MaryMattingly: Ebb of a Spring Tide. She has organized site-specific projects, outdoor installations, and residencies with artists including Matthew Barney, Andrea Carlson, Justin Favela, Martine Gutierrez, Xaviera Simmons, and Tavares Strachan.